Researchers have found that treatment with a Rhodiola Rosea plant extract could be effective for type 2 diabetes management, with potential as an effective and safe alternative to pharmaceuticals.1✅ JOURNAL REFERENCE
DOI: 10.1038/s41598-022-14241-7
The study discovered that in a human type 2 diabetes mouse model, Rhodiola Rosea reduced fasting blood sugar levels, improved insulin injection response, modulated bacteria composition in the gastrointestinal tract, and reduced a number of inflammation biomarkers.
According to the researchers, type 2 diabetes prevalence and related health costs have steadily increased in recent years. People have made use of plants for millennia for the treatment of diseases, and this study reveals that Rhodiola Rosea has promising potential for further analysis.
Existing treatment recommendations include lifestyle changes along with intravenous and oral medications. These medications however have significant side effects or limitations, increasing the need for new treatment options.
The researchers made use of a mouse model that develops high blood sugar, insulin resistance, and obesity, much like advanced type 2 diabetes in humans, to test if glucose homeostasis could be improved with Rhodiola Rosea.
Groups of age-matched female and male mice were randomly allocated to 1 of 2 groups: one group receiving Rhodiola Rosea extract, and a control group receiving water.
The results indicate that Rhodiola Rosea could be beneficial for the treatment of type 2 diabetes, functioning via changes in the microbiome that lead to increased integrity of the gut barrier and reduced inflammatory molecule translocation into the blood circulation.
The integrity of the gut barrier affects insulin response and body weight, and this botanical product could improve the responses of muscle and liver tissues to pancreas-produced insulin.
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